Biomarkers and Occupational Health

This book explores the three basic types of biomarkers (markers of exposure, markers of health effects, and markers of susceptibility to disease) from a variety of perspectives.

Biomarkers and Occupational Health

Biomarkers have emerged as an exciting tool in disease prevention, particularly in the workplace. They may be used to document workers' exposure to toxins, signal the onset of health effects, or identify individuals with susceptibility to certain environmental threats. But the uncertainty is as great as the potential. Are biomarkers suitable for widespread use? How can they be deployed in diverse contexts? How can biological information about workers be handled fairly and ethically? Biomarkers and Occupational Health describes the state of biomarker development, including the implications of the Human Genome program, and presents a range of viewpoints on the future of biomarkers from the leaders in the field. This book explores the three basic types of biomarkers (markers of exposure, markers of health effects, and markers of susceptibility to disease) from a variety of perspectives. It examines what can be learned from well-known exposure sitesâ€"Hiroshima and Nagasaki, Chernobyl, and the Hanford nuclear site in the United States, for exampleâ€"and a wide range of human cases and animal studies. The book also explores the costs and ramifications of developing a large-scale program to monitor potentially exposed workers (e.g., at a cleanup site). A framework is offered for the use of biomarkers based on the mandate to "change the environment before you change the worker." The book explores how to identify ethical issues, how to set development priorities, and how to integrate biomarkers into an occupational health and safety program. The authors present the latest technical findings about markers for chronic beryllium disease as well as markers for exposure to carcinogens, radiation, and chroniumâ€"including prospects for detecting long-past exposures. Biomarkers and Occupational Health offers an update on biomarker development and explores a wide scope of issues. This book will be important to occupational health professionals, biomedical researchers, toxicologists, epidemiologists, and labor and management officials involved in worker health issues. Moritmer L. Mendelsohn, M.D., Ph.D., is Vice-Chairman of the Radiation Effects Research Foundation (RERF) in Japan, which studies the long-term health effects of the atomic blasts in Hiroshima and Nagasaki, and he is former Associate Director of the Lawrence Livermore National Laboratory in California. John P. Peeters, Ph.D., is a geneticist who is currently directing a division of the Office of Occupational Medicine for the United States Department of Energy. Mary Janet Normandy, Ph.D., is a toxicologist who specializes in the metabolism of xenobiotics in mammalian systems. She is currently a member of the Department of Energy's Office of Occupational Medicine.

More Books:

Biomarkers and Occupational Health
Language: en
Pages: 346
Authors: Mary Janet Normandy, John P. Peeters, Mortimer L. Mendelsohn
Categories: Science
Type: BOOK - Published: 1995-02-16 - Publisher: Joseph Henry Press

Biomarkers have emerged as an exciting tool in disease prevention, particularly in the workplace. They may be used to document workers' exposure to toxins, signal the onset of health effects, or identify individuals with susceptibility to certain environmental threats. But the uncertainty is as great as the potential. Are biomarkers
Biomarkers and Occupational Health
Language: en
Pages: 346
Authors: Mary Janet Normandy, John P. Peeters, Mortimer L. Mendelsohn
Categories: Science
Type: BOOK - Published: 1995-01-16 - Publisher: Joseph Henry Press

Biomarkers have emerged as an exciting tool in disease prevention, particularly in the workplace. They may be used to document workers' exposure to toxins, signal the onset of health effects, or identify individuals with susceptibility to certain environmental threats. But the uncertainty is as great as the potential. Are biomarkers
Biomarkers and Occupational Health
Language: en
Pages: 331
Authors: Mortimer L. Mendelsohn, M.D., Ph.D., John P. Peeters, Ph.D., Mary Janet Normandy, Ph.D.
Categories: Science
Type: BOOK - Published: 1995-01-30 - Publisher: Joseph Henry Press

Biomarkers have emerged as an exciting tool in disease prevention, particularly in the workplace. They may be used to document workers' exposure to toxins, signal the onset of health effects, or identify individuals with susceptibility to certain environmental threats. But the uncertainty is as great as the potential. Are biomarkers
Biomarkers and Human Biomonitoring
Language: en
Pages: 498
Authors: Lisbeth Knudsen, Domenico Franco Merlo
Categories: Medical
Type: BOOK - Published: 2011-10-19 - Publisher: Royal Society of Chemistry

Human biomonitoring has developed from a research tool in occupational and environmental health to identify and quantify exposures to harmful substances in urine and blood. The analytical methods for detection of substances in biological media have considerably improved with smaller detection limits and more precise and specific measurements. Human biomonitoring
Encyclopaedia of Occupational Health and Safety: The body, health care, management and policy, tools and approaches
Language: en
Pages: 1174
Authors: Jeanne Mager Stellman
Categories: Electronic books
Type: BOOK - Published: 1998 - Publisher: International Labour Organization

Revised and expanded, this edition provides comprehensive coverage of occupational health and safety. A new CD-ROM version is available which provides the benefits of computer-assisted search capabilities.