Myocardial Protection and the KATP Channel

Since then, an enormous amount of research has been undertaken to characterize it in detail. This volume consolidates both the current knowledge and most recent advances on the subject, and its relationship to myocardial protection.

Myocardial Protection and the KATP Channel

The ATP-sensitive potassium channel (KATP) was discovered in 1983. Since then, an enormous amount of research has been undertaken to characterize it in detail. This volume consolidates both the current knowledge and most recent advances on the subject, and its relationship to myocardial protection. To this end, the editors have assembled investigators at the forefront of ongoing basic and clinical research to provide scholarly and candid comments concerning each of the pertinent issues, including: a comprehensive review of the biology of the channel with respect to the structure-activity relationship as well as overall chemistry of the channel; the role of opening this channel and its effect on smooth muscle (covering both the effects on myocardial stunning and its ability to protect against myocardial infarction); the relationship of KATP channel opening and the protection to the myocardium afforded by the phenomenon of ischemic preconditioning; the relationship between the KATP channel and electrophysiological consequences with specific reference to arrhythmogenicity; and the clinical implications of the use of agents that mimic the opening of this channel, with reference to its protective nature and its use in the treatment of angina. Audience: Clinicians and basic scientists who have a direct interest in the KATP channel as well as those groups who are interested in the entire concept of myocardial protection and its relationship to academic and clinical medicine.

More Books:

Myocardial Protection and the KATP Channel
Language: en
Pages: 214
Authors: Derek Yellon, Garrett J. Gross
Categories: Medical
Type: BOOK - Published: 1995-12-31 - Publisher: Springer Science & Business Media

The ATP-sensitive potassium channel (KATP) was discovered in 1983. Since then, an enormous amount of research has been undertaken to characterize it in detail. This volume consolidates both the current knowledge and most recent advances on the subject, and its relationship to myocardial protection. To this end, the editors have
The Use and Efficacy of a KATP Channel Opener for Myocardial Protection in Cardiac Surgery and Transplantation
Language: en
Pages: 596
Authors: Derek Yellon, Garrett J. Gross
Categories: Medical
Type: BOOK - Published: 2005 - Publisher:

Books about The Use and Efficacy of a KATP Channel Opener for Myocardial Protection in Cardiac Surgery and Transplantation
The Use and Efficacy of a Katp Channel Opener for Myocardial Protection in Cardiac Surgery and Heart Transplantation
Language: en
Pages: 596
Authors: Omal V. Walgama, King's College London. Guy's, King's and St. Thomas's School of Medicine
Categories: Medical
Type: BOOK - Published: 2005 - Publisher:

Books about The Use and Efficacy of a Katp Channel Opener for Myocardial Protection in Cardiac Surgery and Heart Transplantation
Myocardial Viability
Language: en
Pages: 244
Authors: A.E. Iskandrian, Ernst E. van der Wall
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

AMI E. ISKANDRIAN & ERNST E. VAN DER WALL The first edition of this book was published in 1994. Since then important advances have occurred in the field of myocardial viability. This, coupled with increasing interest by the scientific community in the broader issues of its relevance to patient care,
Surgical Options for the Treatment of Heart Failure
Language: en
Pages: 198
Authors: R. Masters
Categories: Medical
Type: BOOK - Published: 2007-12-14 - Publisher: Springer Science & Business Media

Despite the significant decline in heart disease mortaht>' rates over the last 25 years, heart failure has remained a significant problem. We are now confronted with large numbers of terminally ill patients for whom conventional therapies for heart failure have been exhausted and for whom repeated hospital visits are necessary.